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DeCS
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Descriptor English:
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G(M2) Activator Protein
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Descriptor Spanish:
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proteína activadora de G(M2)
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Descriptor Portuguese:
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Proteína Ativadora de G(M2)
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Synonyms English:
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Activator Protein, GM2
GM(2) Activating Protein
GM2 Activator Protein
Hexosaminidase Activator
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Tree Number:
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D08.211.790.249
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Definition English:
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An essential cofactor for the degradation of G(M2)GANGLIOSIDE by lysosomal BETA-N-ACETYLHEXOSAMINIDASES. Genetic mutations resulting in loss of G(M2) activator protein are one of the causes of TAY-SACHS DISEASE, AB VARIANT. |
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History Note English:
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2005(1983)
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Allowable Qualifiers English:
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Record Number:
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38690
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Unique Identifier:
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D049289
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Occurrence in VHL:
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Similar:
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DeCS
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